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生命科学学院(医学遗传学国家重点实验室)

School of Life Sciences,Central South University & State Key Laboratory of Medical Genetics

中南大学生命科学学院学科历史悠久,伴随着百年湘雅医学教育的发展而成长。早在1942年,湘雅医学院就建立了生化科,1943年建立了生物学系,1978年建立了分子生物学系……,这些学科为湘雅的发展和我国医学专门人才的培养发挥着重要作用。2003年5月,在我国著名人...

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4211条记录,
Guidelines for the use and interpretation of assays for monitoring autophagy
WOS被引频次:2039
ESI高被引SCI-E
作者: Klionsky, Daniel J.;Abdalla, Fabio C.;Abeliovich, Hagai;Abraham, Robert T.;Acevedo-Arozena, Abraham;Adeli, Khosrow;Agholme, Lotta;Agnello, Maria;Agostinis, Patrizia;Aguirre-Ghiso, Julio A.;Ahn, Hyung Jun;Ait-Mohamed, Ouardia;Ait-Si-Ali, Slimane;Akematsu, Takahiko;Akira, Shizuo;Al-Younes, Hesham M.;Al-Zeer, Munir A.;Albert, Matthew L.;Albin, Roger L.;Alegre-Abarrategui, Javier
期刊: AUTOPHAGY,2012年8(4):445-544 ISSN:1554-8627
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
WOS被引频次:1131
ESI高被引SCI-E
作者: Klionsky, Daniel J.;Abdelmohsen, Kotb;Abe, Akihisa;Abedin, Md Joynal;Abeliovich, Hagai;Arozena, Abraham Acevedo;Adachi, Hiroaki;Adams, Christopher M.;Adams, Peter D.;Adeli, Khosrow;Adhihetty, Peter J.;Adler, Sharon G.;Agam, Galila;Agarwal, Rajesh;Aghi, Manish K.;Agnello, Maria;Agostinis, Patrizia;Aguilar, Patricia V.;Aguirre-Ghiso, Julio;Airoldi, Edoardo M.
期刊: AUTOPHAGY,2016年12(1):1-222 ISSN:1554-8627
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Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans.
WOS被引频次:376
ESI高被引SCI-EMedline
作者: Zhang, Xinmei;Yeung, Dennis C Y;Karpisek, Michal;Stejskal, David;Zhou, Zhi-Guang;Liu, Feng;Wong, Rachel L C;Chow, Wing-Sun;Tso, Annette W K;Lam, Karen S L;Xu, Aimin
期刊: DIABETES,2008年57(5):1246-1253 ISSN:0012-1797
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Genome sequencing identifies major causes of severe intellectual disability.
WOS被引频次:338
ESI高被引SCI-EMedline
作者: Gilissen, Christian;Hehir-Kwa, Jayne Y.;Thung, Djie Tjwan;van de Vorst, Maartje;van Bon, Bregje W. M.;Willemsen, Marjolein H.;Kwint, Michael;Janssen, Irene M.;Hoischen, Alexander;Schenck, Annette;Leach, Richard;Klein, Robert;Tearle, Rick;Bo, Tan;Pfundt, Rolph;Yntema, Helger G.;de Vries, Bert B. A.;Kleefstra, Tjitske;Brunner, Han G.;Vissers, Lisenka E. L. M.
期刊: Nature,2014年511(7509):344-+ ISSN:0028-0836
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Genome-wide DNA methylation profiling using Infinium (R) assay
WOS被引频次:320
SCI-E
作者: Bibikova, Marina;Le, Jennie;Barnes, Bret;Saedinia-Melnyk, Shadi;Zhou, Lixin;Shen, Richard;Gunderson, Kevin L.
期刊: EPIGENOMICS,2009年1(1):177-200 ISSN:1750-1911
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MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression
WOS被引频次:242
ESI高被引SCI-EEI
作者: Zhou, Ming;Liu, Zixing;Zhao, Yuhua;Ding, Yan;Liu, Hao;Xi, Yaguang;Xiong, Wei;Li, Guiyuan;Lu, Jianrong;Fodstad, Oystein;Riker, Adam I.;Tan, Ming
期刊: Journal of Biological Chemistry,2010年285(28):21496-21507 ISSN:0021-9258
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Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
WOS被引频次:225
ESI高被引SCI-EEI
作者: Amps, Katherine;Andrews, Peter W.;Anyfantis, George;Armstrong, Lyle;Avery, Stuart;Baharvand, Hossein;Baker, Julie;Baker, Duncan;Munoz, Maria B.;Beil, Stephen;Benvenisty, Nissim;Ben-Yosef, Dalit;Biancotti, Juan-Carlos;Bosman, Alexis;Brena, Romulo Martin;Brison, Daniel;Caisander, Gunilla;Camarasa, Marãa V.;Chen, Jieming
期刊: Nature Biotechnology,2011年29(12):1132-U113 ISSN:1087-0156
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SOAPdenovo-Trans: de novo transcriptome assembly with short RNA-Seq reads.
WOS被引频次:225
ESI高被引CPCI-SMedline
作者: Xie, Yinlong;Wu, Gengxiong;Tang, Jingbo;Luo, Ruibang;Patterson, Jordan;Liu, Shanlin;Huang, Weihua;He, Guangzhu;Gu, Shengchang;Li, Shengkang;Zhou, Xin;Lam, Tak-Wah;Li, Yingrui;Xu, Xun;Wong, Gane Ka-Shu;Wang, Jun
期刊: Bioinformatics (Oxford, England),2014年30(12):1660-1666 ISSN:1367-4803
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Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
WOS被引频次:207
ESI高被引SCI-E
作者: Xiong, Hui;Wang, Danling;Chen, Linan;Choo, Yeun Su;Ma, Hong;Tang, Chengyuan;Xia, Kun;Jiang, Wei;Ronai, Ze'ev;Zhuang, Xiaoxi;Zhang, Zhuohua
期刊: JOURNAL OF CLINICAL INVESTIGATION,2009年119(3):650-660 ISSN:0021-9738
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Autophagy in proximal tubules protects against acute kidney injury
WOS被引频次:163
ESI高被引SCI-E
作者: Jiang, Man;Wei, Qingqing;Dong, Guie;Komatsu, Masaaki;Su, Yunchao;Dong, Zheng
期刊: Kidney International,2012年82(12):1271-1283 ISSN:0085-2538
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TGM6 identified as a novel causative gene of spinocerebellar ataxias using exome sequencing
WOS被引频次:146
SCI-EMedline
作者: Wang, Jun Ling;Yang, Xu;Xia, Kun;Hu, Zheng Mao;Weng, Ling;Jin, Xin;Jiang, Hong;Zhang, Peng;Shen, Lu;Guo, Ji Feng;Li, Nan;Li, Ying Rui;Lei, Li Fang;Zhou, Jie;Du, Juan;Zhou, Ya Fang;Pan, Qian;Wang, Jian;Wang, Jun;Li, Rui Qiang
期刊: Brain : a journal of neurology,2010年133(12):3510-3518 ISSN:0006-8950
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Human intracellular ISG15 prevents interferon-alpha/beta over-amplification and auto-inflammation.
WOS被引频次:141
ESI高被引SCI-EMedline
作者: Zhang, Xianqin;Bogunovic, Dusan;Payelle-Brogard, Beatrice;Francois-Newton, Veronique;Speer, Scott D;Yuan, Chao;Volpi, Stefano;Li, Zhi;Sanal, Ozden;Mansouri, Davood;Tezcan, Ilhan;Rice, Gillian I;Chen, Chunyuan;Mansouri, Nahal;Mahdaviani, Seyed Alireza;Itan, Yuval;Boisson, Bertrand;Okada, Satoshi;Zeng, Lu;Wang, Xing
期刊: Nature,2015年517(7532):89-U229 ISSN:0028-0836
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Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma.
WOS被引频次:139
SCI-EMedline
作者: Guo, Guangwu;Gui, Yaoting;Gao, Shengjie;Tang, Aifa;Hu, Xueda;Huang, Yi;Jia, Wenlong;Li, Zesong;He, Minghui;Sun, Liang;Song, Pengfei;Sun, Xiaojuan;Zhao, Xiaokun;Yang, Sangming;Liang, Chaozhao;Wan, Shengqing;Zhou, Fangjian;Chen, Chao;Zhu, Jialou;Li, Xianxin
期刊: Nature genetics,2012年44(1):17-19 ISSN:1061-4036
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Muller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascular leakage.
WOS被引频次:133
SCI-EMedline
作者: Wang, Juanjuan;Xu, Xueliang;Elliott, Michael H.;Zhu, Meili;Le, Yun-Zheng
期刊: DIABETES,2010年59(9):2297-2305 ISSN:0012-1797
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Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol
WOS被引频次:132
SCI-E
作者: Ming Zhou;Yuhua Zhao;Yan Ding;Hao Liu;Zixing Liu;Oystein Fodstad;Adam I Riker;Sushama Kamarajugadda;Jianrong Lu;Laurie B Owen;Susan P Ledoux;Ming Tan
期刊: Molecular Cancer,2010年9(01):1-12 ISSN:1476-4598
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Integrated profiling of microRNAs and mRNAs: microRNAs located on Xq27.3 associate with clear cell renal cell carcinoma.
WOS被引频次:128
SCI-EMedline
作者: Zhou, Liang;Chen, Jiahao;Li, Zhizhong;Li, Xianxin;Hu, Xueda;Huang, Yi;Zhao, Xiaokun;Liang, Chaozhao;Wang, Yong;Sun, Liang;Shi, Min;Xu, Xiaohong;Shen, Feng;Chen, Maoshan;Han, Zujing;Peng, Zhiyu;Zhai, Qingna;Chen, Jing;Zhang, Zhongfu;Yang, Ruilin
期刊: PLOS ONE,2010年5(12):e15224 ISSN:1932-6203
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Direct Conversion of Normal and Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small Molecules.
WOS被引频次:122
ESI高被引SCI-EMedline
作者: Hu, Wenxiang;Qiu, Binlong;Guan, Wuqiang;Wang, Qinying;Wang, Min;Li, Wei;Gao, Longfei;Shen, Lu;Huang, Yin;Xie, Gangcai;Zhao, Hanzhi;Jin, Ying;Tang, Beisha;Yu, Yongchun;Zhao, Jian*;Pei, Gang*
期刊: CELL STEM CELL,2015年17(2):204-212 ISSN:1934-5909
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Immobilization of laccase on magnetic bimodal mesoporous carbon and the application in the removal of phenolic compounds
WOS被引频次:117
SCI-EEIMedline
作者: Yuanyuan Liu;Zhuotong Zeng;Guangming Zeng;Lin Tang;Ya Pang;Zhen Li;Can Liu;Xiaoxia Lei;Mengshi Wu;Pinyun Ren;Zhifeng Liu;Ming Chen;Gengxin Xie
期刊: Bioresource Technology,2012年115(00):21-26 ISSN:0960-8524
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A Hepatic Protein, Fetuin-A, Occupies a Protective Role in Lethal Systemic Inflammation
WOS被引频次:115
SCI-E
作者: Li, Wei;Zhu, Shu;Li, Jianhua;Huang, Yan;Zhou, Rongrong;Fan, Xuegong;Yang, Huan;Gong, Xing;Eissa, N. Tony;Jahnen-Dechent, Willi;Wang, Ping;Tracey, Kevin J.;Sama, Andrew E.;Wang, Haichao
期刊: PLOS ONE,2011年6(2) ISSN:1932-6203
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Metabonomic, transcriptomic, and genomic variation of a population cohort
WOS被引频次:111
SCI-E
作者: Inouye, Michael;Kettunen, Johannes;Soininen, Pasi;Silander, Kaisa;Ripatti, Samuli;Kumpula, Linda S;Hämäläinen, Eija;Jousilahti, Pekka;Kangas, Antti J;Männistö, Satu;Savolainen, Markku J;Jula, Antti;Leiviskä, Jaana;Palotie, Aarno;Salomaa, Veikko;Perola, Markus;Ala‐Korpela, Mika;Peltonen, Leena
期刊: Molecular Systems Biology,2010年6(01) ISSN:1744-4292
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