版权说明 帮助中心
首页 > 成果 > 详情

Prevalence of chronic kidney disease in China: a cross-sectional survey

ESI高被引SCI-EMedline
WOS被引频次:661
认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Zhang, Luxia;Wang, Fang;Wang, Li;Wang, Wenke;Liu, Bicheng;Liu, Jian;Chen, Menghua;He, Qiang;Liao, Yunhua;Yu, Xueqing;Chen, Nan;Zhang, Jian-e;Hu, Zhao;Liu, Fuyou;Hong, Daqing;Ma, Lijie;Liu, Hong;Zhou, Xiaoling;Chen, Jianghua;Pan, Ling;Chen, Wei;Wang, Weiming;Li, Xiaomei;Wang, Haiyan*
通讯作者:
Wang, Haiyan
作者机构:
[Zhang, Luxia; Li, Xiaomei; Wang, Fang; Wang, Haiyan] Peking Univ, Hosp 1, Div Nephrol, Inst Nephrol, Beijing 100871, Peoples R China.
[Wang, Li; Hong, Daqing] Sichuan Acad Med Sci, Div Nephrol, Chengdu, Peoples R China.
[Wang, Li; Hong, Daqing] Sichuan Prov Peoples Hosp, Chengdu, Peoples R China.
[Ma, Lijie; Wang, Wenke] Chifeng Second Hosp, Div Nephrol, Chifeng, Peoples R China.
[Liu, Bicheng; Liu, Hong] Southwest Univ, Zhongda Hosp, Inst Nephrol, Nanjing, Jiangsu, Peoples R China.
通讯机构:
[Wang, Haiyan] Peking Univ, Hosp 1, Dept Med, Div Renal, Beijing 100871, Peoples R China.
语种:
英文
期刊:
The Lancet
ISSN:
0140-6736
年:
2012
卷:
379
期:
9818
页码:
815-822
文献类别:
WOS:Article
所属学科:
ESI学科类别:临床医学;WOS学科类别:Medicine, General & Internal
入藏号:
基金类别:
Ministry of Science and Technology (China) [2007BAI04B10]; Science and Technology Commission of Shanghai [08dz1900502, 07JC14037]; Natural Science Funds of Ning Xia [NZ08102]; Science and Technology Department [30660069]; National Natural Science Foundation of China; Department of Health, Jiangsu Province [H200936]; Sichuan Science and Technology Department [05SG1635]; Ministry of Education (China) [BMU2009131]; International Society of Nephrology Research Committee; China Health and Medical Development Foundation
机构署名:
本校为其他机构
院系归属:
湘雅二医院(第二临床学院)
摘要:
Background: The prevalence of chronic kidney disease is high in developing countries. However, no national survey of chronic kidney disease has been done incorporating both estimated glomerular filtration rate (eGFR) and albuminuria in a developing country with the economic diversity of China. We aimed to measure the prevalence of chronic kidney disease in China with such a survey. Methods: We did a cross-sectional survey of a nationally representative sample of Chinese adults. Chronic kidney disease was defined as eGFR less than 60 mL/min per 1·73 m2 or the presence of albuminuria. Participants completed a lifestyle and medical history questionnaire and had their blood pressure measured, and blood and urine samples taken. Serum creatinine was measured and used to estimate glomerular filtration rate. Urinary albumin and creatinine were tested to assess albuminuria. The crude and adjusted prevalence of indicators of kidney damage were calculated and factors associated with the presence of chronic kidney disease analysed by logistic regression. Findings: 50 550 people were invited to participate, of whom 47 204 agreed. The adjusted prevalence of eGFR less than 60 mL/min per 1·73 m2 was 1·7 (95 CI 1·5-1·9) and of albuminuria was 9·4 (8·9-10·0). The overall prevalence of chronic kidney disease was 10·8 (10·2-11·3); therefore the number of patients with chronic kidney disease in China is estimated to be about 119·5 million (112·9-125·0 million). In rural areas, economic development was independently associated with the presence of albuminuria. The prevalence of chronic kidney disease was high in north (16·9 [15·1-18·7]) and southwest (18·3 [16·4-20·4]) regions compared with other regions. Other factors independently associated with kidney damage were age, sex, hypertension, diabetes, history of cardiovascular disease, hyperuricaemia, area of residence, and economic status. Interpretation: Chronic kidney disease has become an important public health problem in China. Special attention should be paid to residents in economically improving rural areas and specific geographical regions in China. Funding: The Ministry of Science and Technology (China); the Science and Technology Commission of Shanghai; the National Natural Science Foundation of China; the Department of Health, Jiangsu Province; the Sichuan Science and Technology Department; the Ministry of Education (China); the International Society of Nephrology Research Committee; and the China Health and Medical Development Foundation. © 2012 Elsevier Ltd.
参考文献:
Agarwal SK, 2005, NEPHROL DIAL TRANSPL, V20, P1638, DOI 10.1093/ndt/gfh855
Beaglehole R, 2011, LANCET, V377, P1438, DOI 10.1016/S0140-6736(11)60393-0
BELLO AK, 2005, KIDNEY INT S, V98, pS11
Chen N, 2009, NEPHROL DIAL TRANSPL, V24, P2117, DOI 10.1093/ndt/gfn767
Chen W, 2011, NEPHROL DIAL TRANSPL, V26, P1592, DOI 10.1093/ndt/gfq608

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com